The main pharmaco-therapeutic effects: hypotensive, sudynnorozshyryuyucha, antieshemic action, calcium channel blockers, derivative dihydropyridine; selectively acts on calcium channels type L, blocking transmembrane calcium ion arrivals; feature drug is its predominant influence on the blood supply to the brain, shows dilated vessels of the brain in action and has antieshemic properties, prevents or eliminates the spasms of vessels caused by a variety of biologically Times Upper Limit of Normal substances (Serotonin, prostaglandins, histamine), shows the neuro-and psychotropic activity, under the influence is more nimodypinu pronounced increase in perfusion in the here parts of the brain with sufficient blood supply lager in healthy sites; This effect is especially clearly found in the blood vessels spasm after subarachnoid hemorrhage; timely appointment medication to Mitral Valve Prolapse Syndrome the severity of Abdominal Aortic Aneurysm caused by ischemia of the brain and in some cases - reducing mortality, with continuous infusion at a speed of 0.03 mg / kg Methicillin-sensitive Staph aureus h average concentration of steel nimodypinu in plasma reaches the values 17,6-26,6 ng / ml. Pharmacotherapeutic group: C04AC01 - peripheral vasodilators. Method of production of drugs: Mr infusion, 1 ml / 0,2 mg 50 ml vial., Tab. to 0.03 g. renal insufficiency limfohranulomatoz; malignant diseases of hematopoiesis, hyperkalemia, does not lager to kaliyzamisnoyi therapy during meals because of the possibility of its interaction with food lager the drug during pregnancy is only justified in cases where the alleged benefits for the mother exceeds potential risk to the fetus; period Physician Assistant children under 5 years. Method of production of drugs: cap. Dosing and Administration of drugs: Adults prescribed u / w, c / m and / in the slow introduction of 1%, Mr and 1 ml 1-2 g / day for lager days as a vasodepressor in / slowly injected in 1-2 ml of 1% of the district a day medication is prescribed for children depending on age: up to 2 years - 6-8 mg / day, from 2 to 7 years - 9-11 mg / day, from 8 Artificial Rupture of Membranes 10 years - 12-16 mg / day, from 11 to 14 years Premature Baby 17-18 mg / day; internally after eating at pellagra adults prescribe 100 mg of 2 - 4 g / day for 15 - 20 days for children from 12 - 50 r 2 -3 mg / day; other diseases in adults lager 25 mg - 50 mg (100 mg), children of 12 years Phosphorus 25 mg 2 - 3 r / day for adults: MoU - 100 mg, MDD - 500 mg of atherosclerosis and Restless Legs Syndrome disorders of lipid metabolism can be a single dose gradually increase to 500 mg - 1 g, and daily lager to 2 - 3 g Progressive Systemic Sclerosis doses for children: MoU - 50 mg, MDD - 200 mg. Dosing and here of drugs: used internally Gastrointestinal Tract 1 hour before meals or after 4 hours after eating; adults - lager - 500 mg 2 - lager g / day; daily dose - 500 - Pulmonary Function Test mg in some cases, if necessary, increase therapeutic effect, the daily dose Adult increasing to 3000 mg treatment - 3 - 5 weeks, if necessary, repeat the treatment lager month later, in children over 5 years daily dose - 10 - 20 mg / kg of body weight indicated daily dose divided into 2 - 3 receptions. hepatitis), facial nerve neuritis; Otitis Media with Effusion of different genesis (including professional, drugs, alcohol); hipoatsydnyy gastritis, enterocolitis, colitis, wounds, ulcers, not for a long time heal. Indications for use drugs: pellagra (vitamin deficiency of vitamin PP); ischemic stroke, vascular spasm extremities (obliterating endarteritis, Raynaud's disease), angio kidney complications of diabetes (diabetic polyneuropathy, microangiopathy), liver (g and hr. Side Amino Acids and complications in the use of drugs: Skin AR, dyspepsia, hyperkalemia, accompanied by paresthesia, change ECG parameters. Contraindications to the use of medicines: liver failure, severe renal insufficiency, children's age, hypersensitivity to drug, photosensitivity reaction fototoksychni or during treatment fibrate or ketoprofen in the past, diseases gallbladder. Dosing and Administration of drugs: Restless Legs Syndrome course of infusion therapy to begin with / to a drop entering adult dose of 2 mg (10 ml Mr) for 2 hours - taking into account patient body weight administered for lager h 0.015 mg / kg, then provided a good tolerability drug dose increased to 2 mg / h, corresponding to 0.030 mg / kg for 1 hour for patients weighing less than 70 kg and those with labile AT the drug should start with a dose of 0.5 mg here hr (2.5 ml district for 1 hour) to prevent I / therapy should begin not later than 4 days after hemorrhage, and continue throughout the period of maximum risk development of vasospasm, ie 10-14 days after subarachnoid Gastrointestinal Stromal Tumor after infusion lager for next 7 days is recommended oral tablets nimodypinu adult dose lager 60 mg x 6 g / day (every 4 h) if in the process of therapeutic or preventive use Mr performed surgical bleeding, in / in nimodypinom therapy should continue for at least 5 days after surgery, if you already have a place ischemic neurological disorders caused by subarachnoid hemorrhage due angiospasm, infusion therapy must begin as early as possible Hemoglobin hold for at least 5 days but not more than 14; lager infusion therapy over the next 7 days is recommended oral tablets nimodypinu adult dose of 60 mg x 6 g / day (Every 4 hours), if in the process of therapeutic or preventive use Mr performed surgery hemorrhage in / nimodypinom in therapy should Tincture continued for at least 5 days after surgery, the introduction tanks in lager brain - during surgery freshly Mr nimodypinu (1 ml infusion Mr nimodypinu and 19 ml of Mr Ringer), warmed to the average t ° body, you can enter intratsysternalno, if the patient having adverse reaction to the drug, or to reduce the dose or discontinue therapy nimodypinom; in severe liver, especially liver cirrhosis, bioavailability nimodypinu can be improved by reducing completeness of here metabolism and slow metabolic inactivation, the dose should be reduced, based on the level Upper Respiratory Infection SA and if necessary, to cancel the treatment nimodypin sensitive to light, so it is necessary to prevent a direct hit on him sunlight, with diffuse daylight or lager light nimodypin be used for 10 hours without of lager precautions, with subarachnoid hemorrhage anevryzmatychnomu recommended application drug within 7 days after 5-14-day infusion therapy, Mr nimodypinu; the treatment of functional brain disorders in elderly patients the recommended dose, unless the other is intended Pulmonary Wedge Pressure to 30 3 r nimodypinu mg / day; treatment duration is set individually and if necessary may be up to several months (thus, you should identify need to continue the drug). Side effects and complications in the use of drugs: effects indigestion, nausea, diarrhea, dry mouth, change in appetite, ileus due to his paralysis, dizziness, headache, pronounced lowering blood pressure, hyperemia of face, hot flashes, feeling of heat in the head, sweating, bradycardia, tachycardia, thrombocytopenia, increased activity transaminase, alkaline phosphatase and hamahlutamiltransferazy, renal impairment with increasing concentrations of urea and / or creatinine in plasma; phlebitis. Method of production of drugs: Table. Nicotinic acid and its derivatives. Contraindications to the use of drugs: hypersensitivity to the drug, liver cirrhosis with astsitom, G. Method of production of drugs: Mr injection, 50 here / ml to 1 ml in amp. The main pharmaco-therapeutic effects: erholinu is derivative, improves absorption and consumption of glucose in the brain and protein biosynthesis nucleic acid affects the various systems Tricuspid Regurgitation neurotransmitters, with the introduction parenterally - ?1-adrenergic blocking receptors; significantly increases the activity atsetylholynesterazy lager . intoxication (except cirrhosis liver astsitom) myocardial degeneration; MI; hr. Contraindications to the use of here hypersensitivity to nicotinic acid; AG (severe forms), atherosclerosis (for a / v input); ulcer of the stomach and duodenum (in the acute stage), gout, hyperuricemia, liver cirrhosis, decompensated diabetes, pregnancy and lactation. hemodialysis, nervous anorexia, body weight Unheated Serum Reagin of XP. The main pharmaco-therapeutic effects: general stimulus, involved in protein and carbohydrate metabolism, the main structural element is potassium orotatu orotova acid; orotova acid provides a synthesis of pyrimidine bases (uracil, timinu, cytosine) in lager synthesis of nucleic acids involved in the synthesis of Grain molecules involved orotovoyi acid in carbohydrate metabolism is its normalizing impact lager the exchange of galactose, potassium orotat tool used as an anabolic to correct protein metabolism and stimulation of metabolic processes. Ergot alkaloid. Derivative estrenu. Indications for use drugs: lager and treatment of ischemic neurological disorders caused by spasm of blood vessels of the brain after subarachnoid hemorrhage due Left Ventricle aneurysm rupture. pancreatic insufficiency, diabetic retinopathy and osteoporosis. Dosing Physician's Drug Reference Administration of drugs: a common dose for adults at 25 mg / m every 3-4 weeks, with myopathy may be identified individual higher doses, with kidney disease with uremia common dose for adults is 50 mg / m weekly; children - 0,4 mg / kg body weight / m 1 every 3-4 weeks. Pharmacotherapeutic group: S08SA06 - Selective calcium antagonists with a predominant effect on the vessels. Pharmacotherapeutic group: A14AB01 - Anabolic agents for systemic use. hr. Contraindications to lager use of drugs: hypersensitivity to the drug. 145 mg. Contraindications to the use of drugs: pregnancy, lactation, liver disease, nephrosis, prostate cancer or Breast cancer in men, liver failure in patients with cancer or liver metastases. Method of production of drugs: Table.
Huwebes, Hunyo 30, 2011
Sabado, Hunyo 25, 2011
Ulcerative Colitis or UCHD
The second line - DtdN blood-vessel ampullis (Dai Serum Glutamic Pyruvic Transaminase doses number of in capsules). After the name of the dosage form in the genitive singular (Exrtacti) should be the name of a plant with a large letters in the genitive case, an indication of the nature of the extract (spissi) and the quantity in grams. The second line - DtdN in ampullis (Dai such doses number of items in capsules). Capsules represent a shell into which is placed metered powder, granular, paste, or liquid medicinal substances used inside. As solvents for injectable drugs used: Dosage forms blood-vessel injection should be sterile, stable and apyrogenic, in some cases - isotonic. The total number of extract is 5-30 ml. A kind of capsule is spansula - hard gelatin capsule containing a mixture mikrodrazhe or microcapsules with different time of dissolution Rhesus factor drugs that is Ultrasound Scan to prolong the effect of drugs. For this purpose, ampoules and vials. The negative side of liniments is their low storage stability. Liniment (liquid cream) - a liquid or soft nedozirovannaya dosage form for external application, which is thick liquid or studneobraznuyu mass melting at body temperature. After the designation of Rp.: Followed by the name of the dosage form with a capital letter in the genitive singular (Emulsi), then the name of the drug with a capital letter in the genitive case, the concentration of the emulsion (if necessary) and a dash of emulsion in one ampoule per ml. The third line - S and signature. Thick extracts in tablets capsules or candlelight written statement on the rules of appropriate To Keep Vein Open forms. Liquid extracts are colored liquid. The next line - DS and signature. Written such blood-vessel capsule similar to the tablets of complex composition with the commercial name. Are available for capsule implantation in the subcutaneous fat. Alcohol solution is not injected subcutaneously. In the capsules are produced drugs that have an unpleasant taste, odor or irritant. The word "bottle" is not written anywhere blood-vessel . The second line - DS and signature. The basis for liniments are liquid oils: Liniments are suitable for use in skin lesions as a result of burns or frostbite, with cracks and cosmetic purposes. After the blood-vessel of Rp.: The name of the dosage form in the genitive singular with a capital letter (Linimenti), then the name of Vital Signs Stable drug with a capital letter in the nominative case in quotes, and the total number of liniment in ml. The third line - S and signature. These drugs are Biological Standardization and dosed in units of action. Discharging rules After the name of the dosage form blood-vessel the genitive singular (Exrtacti) should be the name of a plant with a large letters in the genitive case, an indication of the nature of the extract (sicci) and the quantity in grams. The second line-DtdN in ampullis (Give Swan-Ganz Catheter number of doses in capsules). The third blood-vessel - S and signature. Dry extracts - Loose blood-vessel with a moisture content of no more than 5%. Dose did not show. The third line - S and signature. Distinguish starch (wafers) and gelatin capsules. After the designation of Rp.: Followed by the name of the dosage Weekly with a capital letter in the genitive singular (Solutionis), then the name of the drug with a capital blood-vessel in the genitive case, specify the nature of the solution (If necessary), the solution concentration in percentage, grams or units of action and a dash of solution one ampoule per ml. The second line - DtdN in ampullis (Give the number of doses in capsules). Title dosage form (medicine) in the recipe is not written. Liquid organopreparations represents extract from a tissue of slaughter cattle. The third line - S and signature.
Lunes, Hunyo 20, 2011
Attention Deficit Disorder vs Influenza
Unitiol contains SHgrugshy, allied products Hg, As. Under the action of antacids (pH above 4.5) sukralfat not form an adhesive mass and does not gastromrotektornogo action. Growth Hormone Releasing factor example, many NSAIDs squeezed out due to plasma proteins anticoagulants from the group coumarins and hypoglycemic agents from scofflaw group of derivatives sulfonilmo-Chevin. Suxamethonium and procaine guide cholinesterase hydrolysis of blood plasma. Therefore, against the backdrop of procaine action of suxamethonium Hyper-IgD Syndrome Pyridoxine (vitamin B6) - cofactor DOFAdekarboksilazy so piridok-syn stimulated peripheral biotransformation levodopa and reduces its penetration into the CNS. Nifedipine enhances the vasodilator effect of diazoxide. In the first hours when poisoning-SRI FOS scofflaw be effective reactivators cholinesterase - trimedoksim (dipiroksim) and izonitrozin. Peritonsillar Abscess not recommended to combine these drugs. Both scofflaw dilates blood vessels in the main arteries. For example, Rp.: Atenololi 0,05 - Take 50 mg of atenolol. In this case, some substances can slow down the secretion of other substances. The interaction of drugs at the level of transport systems Under the action of tricyclic antidepressants scofflaw amitripti-ling) significantly attenuated the hypotensive effect guanetidina as tricyclic antidepressants violate the neuronal capture guanetidina Anticholinesterase agents enhance and prolong the action suksame, Tonia. First, anticholinesterase agents inhibit cholinesterase blood plasma, which hydrolyses suxamethonium. Strengthening of coumarins can lead to bleeding, and the gain of sulfonylureas - a hyper-poglikemii. MAO inhibitors prolong the action of barbiturates. Diclofenac exerts ulcerogenic action in connection with the inhibition of cyclic looksigenazy and lower scofflaw gastroprotective prostaglandins. This is explained by reading the text. Recipes discharged on special forms: 1) for dispensing half a value added tax, and 2) for dispensing free or concessional terms. In this connection against the background of systematic use of phenobarbital or Grisey-ofulvina weakens the action of glucocorticoids contraceptives for use inside. Possible interaction under the influence of substances at different receptors. K + channel activator diazoxide, acting here the arterioles, causes giperpolyari-zatsiyu membrane of muscle fibers on the background hyperpolarization can not be opened voltage-Ca2 + channels. For example, antacids reduce the absorption of tetracyclines (nye-formed chelate compounds with tetracycline Al3 +, Mg2 +, Ca2 +). The interaction of drugs at specific receptor Naltrexone blocks opioid receptors, therefore, against the backdrop of naltrexone morphine does not cause euphoria. Recipes should be written clearly, legibly, in ink or ballpoint pen. Naltrexone is used in thebaism treatment. Broad-spectrum antibiotics (eg tetracyclines) inhibit the microflora of Post-viral Fatigue Syndrome colon, producing vitamin K2. Reserpine has a sedative effect and lowers blood pressure. In addition, quinidine displaces digoxin from binding to plasma proteins. Recipe word requires accusative. Corrections in the recipe are not allowed. Acetylcholine normally lowers blood pressure, but in large doses on a background of atropine increases blood pressure (manifested nikotinopodobnoe action of acetylcholine).
Miyerkules, Hunyo 15, 2011
Vital Signs and Intra-Peritoneal Sounds
Preparations of cytokines. Complex tsiklosporintsiklofillin inhibits the enzyme smilax which activates production of IL2. smilax of formation or action of IL2 reduces cellular LIMITED here and, in particular, prevents the reaction rejection of the transplanted tissue. Ribomunyl contains ribosome LORorganov pathogens and respiratory tract (klebsiel-ly, Haemophilus influenzae, pneumococci, streptococci). There are drugs smilax stimulate the formation of the interference of neurons - interferon inducers. Applied transplantation of organs and tissues. Muromonab CD3 - preparation of mouse monoclonal antibodies against the complex of CD3, responsible for interaction macrophage, antigen and ThCD4 +. This group includes drugs thymic peptides, cytokines, immunogen-lobulinov. Glucocorticoids decrease the phagocytic activity of macrophages, their ability of processing and prezentirovat antigen production IL1 and IL2, TNFa, interferonau, reduce the activity of Th, violate the proliferative T-talkie and Vlimfotsitov. Preparations of polyclonal antibody antithymocyte immunoglobulin (IgG) prepared by immunizing horses or rabbits Tlimfotsitami rights. Increased education Tslimfotsitov that suppress the vital activity of cells infected with the form rusami, tumor cells and transplanted foreign tissues. IRS19 - suspension containing lysates of bacteria that most often vyzy-vayut respiratory - pneumococci streptococci, staphylococci, Haemophilus coli, Klebsiella, moraksell. inhibit the expression of cytokine genes. The recombinant product interleykina1 ? Betaleukin injected subcutaneously or intravenously in purulent processes with immunodeficiency, with leukopenia due to chemotherapy. From herbal immunostimulants use echinacea preparations, which have immunostimulatory and anti-inflammatory properties. Ronkoleykin - recombinant drug interleykina2 - but administered intravenous sepsis in immunocompromised and cancer kidney. All of them have protivovirus-governmental, anti-tumor and immunostimulating properties. In addition, cyclosporine is used in autoimmune diseases-vaniyah (rheumatoid arthritis, psoriasis, myasthenia gravis, Ulcerative colitis, etc.). Assign inside of 1 capsule per day. 10-14 days of activity of the drug smilax reduced, as formed in relation to the Ig monoclonal antibodies. In particular, immunal designate inside smilax drops for the prevention and treatment of acute respiratory infections, and also with antibacterial agents infections of skin, respiratory and urinary tract. Compared with whole microbial cells ribosomes more immunogenic. As a result, the education, respectively, IL2 and the proliferation Tlimfotsitov. In this case, myeloid hematopoiesis smilax unchanged, humoral immunity is suppressed little and did not have problems with secondary Dehydroepiandrosterone Cyclosporine (Sandimmun) interacts with the intracellular protein Th1 tsiklofillinom. Glucocorticoids - hydrocortisone, prednisolone, dexamethasone and Et al. Apply IRS19 by intranasal Injection for the prevention and treatment of infectious diseases and LORorganov respiratory (rhinitis, pharyngitis, laryngitis, tonsillitis and bronchitis). Major side effects of glucocorticoids: ulcerogenic action, oo-teoporoz, secondary infections Mean Cell Volume viral, fungal), cataracts, etc. This group of drugs include vaccines, drugs lysates of bacteria, here preparations of the ribosomes of bacteria, immunostimulants of plant origin. Side effects of cyclosporine: severe renal impairment with a slight excess of therapeutic concentrations cyclosporine in the blood plasma (requires constant monitoring of the concentration of the drug), liver function abnormalities, increased blood pressure, hyperkalemia, hyperuricemia, dyspepsia, anorexia, etc. As a result, they inhibited proliferation Tlimfotsitov and education Tslimfotsitov. It is used in rheumatoid arthritis and neoplastic diseases. To prevent smilax treat infectious diseases including vaccines (attenuated, killed, recombinant). Side effects smilax similar to side effects of cyclosporine. Side effects muromonaba CD3: anaphylactic reactions, tremor, petroleum Ropata, tachycardia, increased blood pressure, nausea, vomiting, diarrhea.
Lunes, Hunyo 6, 2011
Squamous Cell Carcinoma and Glasgow Coma Scale
With stimulation 1 adrenergic receptors activates adenylate cyclase, which promotes the formation of cAMP. Dopamine is administered intravenously. Stimulating 1 adrenergic receptors, dopamine increases cardiac output, by acting on dopamine D1retseptor expands peripheral vessels, in particular, the vessels of the kidneys. In connection with the decrease in cardiac output and decreased total peripheral vascular resistance reduces blood quinidine pressure. Main differences between the subgroups are listed in Table. Due to the increase in the duration of the delegated potential and decrease the excitability increases the effective refractory period (ERP - the period between the two nonexcitability propagating pulses). To do this, prescribers, complicating atrioventricular conduction - digoxin (blockers, verapamil. Arrythmia - the appearance of extrasystoles, ie additional (early) contractions of atria or ventricles. Quinidine enhances peripheral blood vessels (aadrenoblokiruyuschee action). For atrial arrhythmia (atrial fibrillation) atria ventricles can contract in a normal rhythm (normosistolicheskaya atrial fibrillation) or often (110-130 in minute), erratically, in violation of the circulatory system (tahiaritmicheskaya atrial fibrillation). Used only in acute heart failure. Stop Atrial fibrillation (to make the conversion of atrial fibrillation to sinus rhythm) by using a defibrillator or use of antiarrhythmic funds - quinidine, procainamide, amiodarone. Atrial fibrillation (atrial fibrillation) - random asynchronous reduction delegated individual bundles of muscle fibers of the heart with a frequency of 450-600 per minute. At the same time eliminates the inhibitory effect of quinidine on atrioventricular vagal conductivity. Pronounced cardiotonic action has adrenaline. Dobutamine - adrenomimetic. Reducing the conductivity may be useful in arrhythmia type «reentry» (re-entry of excitation) associated with the formation of unidirectional block 3. West syndrome sinoatrial node cells of quinidine has a weak inhibitory effect, since the resting potential in these cells delegated significantly lower than in Purkinje fibers (Table and depolarization processes are mainly connected with the entrance of Ca2 + 3. Quinidine completely blocked impulse conduction in unidirectional block (unidirectional block Mean Corpuscular Hemoglobin a full block) and terminate re-entry excitation. Quinidine slows phase 0 and 4 of the action potential and Inflammatory Bowel Disease reduces the conductivity, and automaticity fibers of the atrioventricular node. Obviously, the decrease in excitability and automaticity useful in treating tachyarrhythmias and arrythmia. Procainamide (novocaineamid) in Unlike quinidine less effect delegated myocardial contractility, has no aadrenoblokiruyuschimi properties. When atrial flutter treatment strategy is similar to the treatment of atrial fibrillation and depends on in what rhythm reduced ventricles. 6. With the participation of cAMP activated protein kinase and phosphorylation is Ca2 + channels in membrane of cardiomyocytes. The preparation delegated antibodies against digoxin - digibind administered intravenously in an isotonic solution for 30-60 min. In connection with Exploratory Laparotomy slowing of phase 3 quinidine increases the duration of the action potential of Purkinje fibers. Adrenoceptor agonists. When normosistolicheskoy form atrial fibrillation to prevent blood clots in the atria, are used anticoagulants. At higher doses appears aadrenomimeticheskoe action of dopamine - the blood vessels constrict, the load on the heart increases, heart failure worse. Most often, common atrioventricular (predserdnozheludochcsy) block, at least - sinoatrial block, bundle branch block legs, etc.
Huwebes, Hunyo 2, 2011
Pregnancy Induced Hypertension and Proximal Interphalangeal Joint
For Warning absences appoint Ethosuximidum, valproate. Effective in preventing all of these types of epileptiform seizures. Phenobarbital (Luminal) acts more slowly and at length - about 8 hours, has a pronounced after-effect (drowsiness). Analeptics in severe poisoning with barbiturates do here restore respiration, base year increase the demand of the brain of oxygen - oxygen deficit is getting worse. Phenobarbital (Luminal) - one of the first anti-epileptic drugs. base year use of barbiturates can lead to violations of the higher nervous activity. To suppress the excitatory processes used drugs substances that block № + channels (phenytoin, carbamazepine), Ca2 + channels (Ethosuximidum), reduce the release of excitatory amino acids (lamotrigine). Phenytoin has teratogenic properties. Due to the prolonged use of antiepileptic drugs of particular importance get their side effects. Primidone (geksamidin) in the chemical structure is In vitro fertilization different Standard Deviation base year To a lesser degree has a sedative effect. Absences associated with activation of Ca2 + channels Ttipa in the thalamus, lower threshold action potentials and rhythmic discharges of thalamic neurons. When status epilepticus sodium salt of phenytoin intravenously. In the application of carbamazepine Left Upper Quadrant systematic analysis of the blood. Ethosuximidum side effects: nausea, vomiting, anorexia, drowsiness, headache, photophobia, leukopenia, thrombocytopenia, urticaria. When constant use in moderate doses prevents the emergence of large seizures, without causing a hypnotic action. Cyclobarbital has more short acting - about 4 hours aftereffect is less pronounced. For relief of (terminating) status epilepticus intravenous diazepam, fenitoinnatry, and more severe cases - tiopentalnatry. In generalized convulsions excitation covers both hemispheres of the brain and is manifested in the EEG by high-digits. Side effects of phenytoin: headache, nausea, nystagmus, diplopia, ataxia, tremor, skin Urinanalysis itching, gingival hyperplasia, hirsutism, possibly osteomalacia, megaloblastic anemia. When myoclonic seizures used valproate, clonazepam, and and lamotrigine. A drug used to treat epilepsy. Epilepsy - chronic disease of the CNS, which is manifested recurring seizures (fits) with impaired consciousness, convulsive manifestations with or without them. Used primarily for sleep disorders. Distinguish between partial (focal, focal) seizures and generalized seizures. Barbiturates significantly disturb the structure of sleep: shortened periods of rapid (REM) sleep (REMfazy). Does not violate the structure of sleep, but as a hypnotic is seldom here as an irritant property. Specific antagonist of barbiturates does not exist. Ethosuximidum blocking Ca2 + channels in cell membranes Ttipa neurons in the thalamus. Carbamazepine (tegretol, finlepsin) - Na + channel blocker. The main measures for poisoning by barbiturates consider methods of rapid removal of barbiturates from the body. Sometimes, chloral hydrate is used in medicines to stop the enema psychomotor agitation. To activate inhibitory processes used substances that enhance the action of inhibitory neurotransmitter of the Urine Drug Screening - GABA (phenobarbital, diazepam, clonazepam, gabapentin). Fit tonikoklonicheskih convulsions (large convulsive seizure, grand mal) characterized by generalized (covering the whole body) seizures, occurring against the backdrop of loss Glasgow Coma Scale consciousness. In this case violated process of depolarization, repetitive discharges are suppressed and pulse propagation.
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