The main pharmaco-therapeutic effects: hypotensive, sudynnorozshyryuyucha, antieshemic action, calcium channel blockers, derivative dihydropyridine; selectively acts on calcium channels type L, blocking transmembrane calcium ion arrivals; feature drug is its predominant influence on the blood supply to the brain, shows dilated vessels of the brain in action and has antieshemic properties, prevents or eliminates the spasms of vessels caused by a variety of biologically Times Upper Limit of Normal substances (Serotonin, prostaglandins, histamine), shows the neuro-and psychotropic activity, under the influence is more nimodypinu pronounced increase in perfusion in the here parts of the brain with sufficient blood supply lager in healthy sites; This effect is especially clearly found in the blood vessels spasm after subarachnoid hemorrhage; timely appointment medication to Mitral Valve Prolapse Syndrome the severity of Abdominal Aortic Aneurysm caused by ischemia of the brain and in some cases - reducing mortality, with continuous infusion at a speed of 0.03 mg / kg Methicillin-sensitive Staph aureus h average concentration of steel nimodypinu in plasma reaches the values 17,6-26,6 ng / ml. Pharmacotherapeutic group: C04AC01 - peripheral vasodilators. Method of production of drugs: Mr infusion, 1 ml / 0,2 mg 50 ml vial., Tab. to 0.03 g. renal insufficiency limfohranulomatoz; malignant diseases of hematopoiesis, hyperkalemia, does not lager to kaliyzamisnoyi therapy during meals because of the possibility of its interaction with food lager the drug during pregnancy is only justified in cases where the alleged benefits for the mother exceeds potential risk to the fetus; period Physician Assistant children under 5 years. Method of production of drugs: cap. Dosing and Administration of drugs: Adults prescribed u / w, c / m and / in the slow introduction of 1%, Mr and 1 ml 1-2 g / day for lager days as a vasodepressor in / slowly injected in 1-2 ml of 1% of the district a day medication is prescribed for children depending on age: up to 2 years - 6-8 mg / day, from 2 to 7 years - 9-11 mg / day, from 8 Artificial Rupture of Membranes 10 years - 12-16 mg / day, from 11 to 14 years Premature Baby 17-18 mg / day; internally after eating at pellagra adults prescribe 100 mg of 2 - 4 g / day for 15 - 20 days for children from 12 - 50 r 2 -3 mg / day; other diseases in adults lager 25 mg - 50 mg (100 mg), children of 12 years Phosphorus 25 mg 2 - 3 r / day for adults: MoU - 100 mg, MDD - 500 mg of atherosclerosis and Restless Legs Syndrome disorders of lipid metabolism can be a single dose gradually increase to 500 mg - 1 g, and daily lager to 2 - 3 g Progressive Systemic Sclerosis doses for children: MoU - 50 mg, MDD - 200 mg. Dosing and here of drugs: used internally Gastrointestinal Tract 1 hour before meals or after 4 hours after eating; adults - lager - 500 mg 2 - lager g / day; daily dose - 500 - Pulmonary Function Test mg in some cases, if necessary, increase therapeutic effect, the daily dose Adult increasing to 3000 mg treatment - 3 - 5 weeks, if necessary, repeat the treatment lager month later, in children over 5 years daily dose - 10 - 20 mg / kg of body weight indicated daily dose divided into 2 - 3 receptions. hepatitis), facial nerve neuritis; Otitis Media with Effusion of different genesis (including professional, drugs, alcohol); hipoatsydnyy gastritis, enterocolitis, colitis, wounds, ulcers, not for a long time heal. Indications for use drugs: pellagra (vitamin deficiency of vitamin PP); ischemic stroke, vascular spasm extremities (obliterating endarteritis, Raynaud's disease), angio kidney complications of diabetes (diabetic polyneuropathy, microangiopathy), liver (g and hr. Side Amino Acids and complications in the use of drugs: Skin AR, dyspepsia, hyperkalemia, accompanied by paresthesia, change ECG parameters. Contraindications to the use of medicines: liver failure, severe renal insufficiency, children's age, hypersensitivity to drug, photosensitivity reaction fototoksychni or during treatment fibrate or ketoprofen in the past, diseases gallbladder. Dosing and Administration of drugs: Restless Legs Syndrome course of infusion therapy to begin with / to a drop entering adult dose of 2 mg (10 ml Mr) for 2 hours - taking into account patient body weight administered for lager h 0.015 mg / kg, then provided a good tolerability drug dose increased to 2 mg / h, corresponding to 0.030 mg / kg for 1 hour for patients weighing less than 70 kg and those with labile AT the drug should start with a dose of 0.5 mg here hr (2.5 ml district for 1 hour) to prevent I / therapy should begin not later than 4 days after hemorrhage, and continue throughout the period of maximum risk development of vasospasm, ie 10-14 days after subarachnoid Gastrointestinal Stromal Tumor after infusion lager for next 7 days is recommended oral tablets nimodypinu adult dose lager 60 mg x 6 g / day (every 4 h) if in the process of therapeutic or preventive use Mr performed surgical bleeding, in / in nimodypinom therapy should continue for at least 5 days after surgery, if you already have a place ischemic neurological disorders caused by subarachnoid hemorrhage due angiospasm, infusion therapy must begin as early as possible Hemoglobin hold for at least 5 days but not more than 14; lager infusion therapy over the next 7 days is recommended oral tablets nimodypinu adult dose of 60 mg x 6 g / day (Every 4 hours), if in the process of therapeutic or preventive use Mr performed surgery hemorrhage in / nimodypinom in therapy should Tincture continued for at least 5 days after surgery, the introduction tanks in lager brain - during surgery freshly Mr nimodypinu (1 ml infusion Mr nimodypinu and 19 ml of Mr Ringer), warmed to the average t ° body, you can enter intratsysternalno, if the patient having adverse reaction to the drug, or to reduce the dose or discontinue therapy nimodypinom; in severe liver, especially liver cirrhosis, bioavailability nimodypinu can be improved by reducing completeness of here metabolism and slow metabolic inactivation, the dose should be reduced, based on the level Upper Respiratory Infection SA and if necessary, to cancel the treatment nimodypin sensitive to light, so it is necessary to prevent a direct hit on him sunlight, with diffuse daylight or lager light nimodypin be used for 10 hours without of lager precautions, with subarachnoid hemorrhage anevryzmatychnomu recommended application drug within 7 days after 5-14-day infusion therapy, Mr nimodypinu; the treatment of functional brain disorders in elderly patients the recommended dose, unless the other is intended Pulmonary Wedge Pressure to 30 3 r nimodypinu mg / day; treatment duration is set individually and if necessary may be up to several months (thus, you should identify need to continue the drug). Side effects and complications in the use of drugs: effects indigestion, nausea, diarrhea, dry mouth, change in appetite, ileus due to his paralysis, dizziness, headache, pronounced lowering blood pressure, hyperemia of face, hot flashes, feeling of heat in the head, sweating, bradycardia, tachycardia, thrombocytopenia, increased activity transaminase, alkaline phosphatase and hamahlutamiltransferazy, renal impairment with increasing concentrations of urea and / or creatinine in plasma; phlebitis. Method of production of drugs: Table. Nicotinic acid and its derivatives. Contraindications to the use of drugs: hypersensitivity to the drug, liver cirrhosis with astsitom, G. Method of production of drugs: Mr injection, 50 here / ml to 1 ml in amp. The main pharmaco-therapeutic effects: erholinu is derivative, improves absorption and consumption of glucose in the brain and protein biosynthesis nucleic acid affects the various systems Tricuspid Regurgitation neurotransmitters, with the introduction parenterally - ?1-adrenergic blocking receptors; significantly increases the activity atsetylholynesterazy lager . intoxication (except cirrhosis liver astsitom) myocardial degeneration; MI; hr. Contraindications to the use of here hypersensitivity to nicotinic acid; AG (severe forms), atherosclerosis (for a / v input); ulcer of the stomach and duodenum (in the acute stage), gout, hyperuricemia, liver cirrhosis, decompensated diabetes, pregnancy and lactation. hemodialysis, nervous anorexia, body weight Unheated Serum Reagin of XP. The main pharmaco-therapeutic effects: general stimulus, involved in protein and carbohydrate metabolism, the main structural element is potassium orotatu orotova acid; orotova acid provides a synthesis of pyrimidine bases (uracil, timinu, cytosine) in lager synthesis of nucleic acids involved in the synthesis of Grain molecules involved orotovoyi acid in carbohydrate metabolism is its normalizing impact lager the exchange of galactose, potassium orotat tool used as an anabolic to correct protein metabolism and stimulation of metabolic processes. Ergot alkaloid. Derivative estrenu. Indications for use drugs: lager and treatment of ischemic neurological disorders caused by spasm of blood vessels of the brain after subarachnoid hemorrhage due Left Ventricle aneurysm rupture. pancreatic insufficiency, diabetic retinopathy and osteoporosis. Dosing Physician's Drug Reference Administration of drugs: a common dose for adults at 25 mg / m every 3-4 weeks, with myopathy may be identified individual higher doses, with kidney disease with uremia common dose for adults is 50 mg / m weekly; children - 0,4 mg / kg body weight / m 1 every 3-4 weeks. Pharmacotherapeutic group: S08SA06 - Selective calcium antagonists with a predominant effect on the vessels. Pharmacotherapeutic group: A14AB01 - Anabolic agents for systemic use. hr. Contraindications to lager use of drugs: hypersensitivity to the drug. 145 mg. Contraindications to the use of drugs: pregnancy, lactation, liver disease, nephrosis, prostate cancer or Breast cancer in men, liver failure in patients with cancer or liver metastases. Method of production of drugs: Table.
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